2015/12/24 上午10:24:28 星期四
特别鸣谢86361班校友捐赠制作环境与生物工程学院网站
师资队伍

徐 渊

徐 渊

个人简介

男,生于198805月,汉族。

2015年于中国药科大学获得理学博士学位。

E-mail xjwshxy@126.com           

教育经历

2006.09 –2010.06   中国药科大学本科药物制剂

2010.09 –2012.06   中国药科大学硕士药理学

2010.09 –2015.12   中国药科大学博士药理学

研究方向

1. 天然产物生理活性组分筛选与评价。

2. 炎症相关药物的作用机制研究。

3. 抗肿瘤药物的作用机制研究

发表文章

1. Xu Y, Xu Y, Wang Y, Wang Y, He L, Jiang Z, Huang Z, Liao H, Li J, Saavedra JM, Zhang L, Pang T. Telmisartan prevention of LPS-induced microglia activation involves M2 microglia polarization via CaMKKβ-dependent AMPK activation. Brain Behavior and Immunity. 2015; 50:298-313. (IF: 5.874)

2. Xu Y, Wang Y, Jiang Z, Zhang L, Wang T. Triptolide reduces prostate size and androgen level on testosterone-induced benign prostatic hyperplasia in Sprague Dawley rats. Chinese journal of natural medicines. 2016. Accept. (IF: 1.382)

3. Shi J#, Xu Y#, Wang X, Zhang L, Zhu J, Pang T, Bao X. Synthesis and evaluation of a novel Rhodamine B pyrene (2) rotaxane as an intracellular delivery agent for doxorubicin. Organic & biomolecular chemistry. 2015; 13:7517-7529. (IF:3.559)

4. Wang Y#, Xu Y#, Guerram M, Wang B, Zhu X, Jiang Z, Zhang L. Deoxypodophyllotoxin induces G2/M cell cycle arrest and apoptosis in SGC-7901 cells and inhibits tumor growth in vivo. Molecules. 2015; 20:1661-1675. (IF: 2.465)

5. Shen H#, Xu Y#, Jiang Z, Huang X, Zhang L, Wang T. Inhibitory effects of Tripterygium wilfordii multiglycoside on benign prostatic hyperplasia in rats. Chinese journal of natural medicines. 2015; 13:421-427. (IF: 1.382) (共同一作)

6. Xu Y, Wang Y, Xu Y, Li J, Liao H, Zhang L, Pang T. Development of a Novel Phosphorylated AMPK Protection Assay for High-Throughput Screening Using TR-FRET Assay. Journal of biomolecular screening. 2015; 20:906-912.(IF: 2.218)

7. Wang Y, Gao Y, Gao W, Xu Y, Xu Y, Wang Y, Chang S, Yu L, Zhang L, Liao H, Yang L, Pang T, Qiu W. Design, synthesis and biological evaluation of tricyclic diterpene derivatives as novel neuroprotective agents against ischemic brain injury. European journal of medicinal chemistry. 2015; 103:396-408. (IF: 3.902)

8. Bao X, Cao Q, Xu Y, Gao Y, Xu Y, Nie X, Zhou B, Pang T, Zhu J. Synthesis and evaluation of a new Rhodamine B and Di(2-picolyl)amine conjugate as a highly sensitive and selective chemosensor for Al3+ and its application in living-cell imaging. Bioorganic & medicinal chemistry. 2015; 23:694-702. (IF: 2.923)

9. Ye Q, Mao W, Zhou Y, Xu L, Li Q, Gao Y, Wang J, Li C,Xu Y, Xu Y, Liao H, Zhang L, Gao J, Li J, Pang T. Synthesis and biological evaluation of 3 - ((1,2,4)triazolo(4,3-a)pyridin-3-yl) - 4 - (indol-3-yl) - maleimides as potent, selective GSK-3β inhibitors and neuroprotective agents. Bioorganic & medicinal chemistry. 2015; 23:1179-1188.(IF: 2.923)

10. Ye Q, Li Q, Zhou Y, Xu L, Mao W, Gao Y, Li C, Xu Y, Xu Y, Liao H, Zhang L, Gao J, Li J, Pang T. Synthesis and Evaluation of 3 - (furo(2,3-b)pyridin-3-yl) - 4 - (1H-indol-3-yl) - maleimides as Novel GSK-3β Inhibitors and Anti-Ischemic Agents. Chemical biology & drug design. 2015; 86:746-752. (IF: 2.802)

11. Li J, Li J, Xu Y, Wang Y, Zhang L, Ding L, Xuan Y, Pang T, Lin H. Asymmetric synthesis and biological activities of natural product (+) - balasubramide and its derivatives. Natural product research. 2016; 30:800-805. (IF: 1.057)