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贾爱群

2018-08-27来源:环境科学与生物工程学院作者:审核人:环境与生物工程学院编辑:阅读:907

贾爱群——教授 博士生导师

性别:男;出生年月:1969.7最后学位:博士

联系方式:

南京理工大学环境与生物工程学院,南京,210094

电话:025-84303216

邮箱:jiaaiqun@gmail.com

教育背景:

2001.1-2004.7  中国科学院昆明植物研究所,理学博士(植物化学)

1998.9-2001.1  无锡轻工大学(今江南大学),工学硕士(应用化学)

1989.9-1993.7  河南师范大学,理学学士(化学)

工作经历:

2012.5至今    南京理工大学环境与生物工程学院,博士生导师

2012.4至今    南京理工大学环境与生物工程学院生物工程系,教授

2008.2-2009.3   德国马普学会耶拿化学生态研究所,博士后

2006.7-2012.4   南京理工大学,副教授

2005.12-2006.7  香港中文大学,Research Associate

2004.7-2005.12  江苏正大天晴制药,新药研发工程师

1993.7-1998.7   洛阳师专(今洛阳师范学院)化学系,助教-讲师

研究兴趣:

有重要生理活性天然产物的研究与开发。

  • 国内外特色(海洋)(食)生物资源中(新颖结构)有机化合物的发现与重要生理活性评价

  • 基于新合成方法的有重要生理活性天然有机化合物的化学修饰

  • 功能天然有机小分子的化学生态学或化学生物学行为研究

学术任职:

  • 中国化学会永久会员

  • 中国植物学会会员

  • The Journal of Medicinal Plant Research, Journal of Medicinal Food Plos One, Bioorganic & Medicinal Chemistry Letters, Natural Product Research, Scientific Reports, Chinese Journal of Catalysis, Food Chemistry, Chemosphere等国际期刊审稿人

  • BMC Complementary & Alternative MedicineIF2.288)副主编,Frontiers in Cellular and Infection MicrobiologyIF4.300)编委

近年来主持研究项目:

  • 基于C-H活化策略的海洋二酮哌嗪的衍生化及其细菌群体感应信号传导,国家自然科学基金(地区),(2018-2021

  • 广西珍稀药食同源植物金花茶花叶中功能因子的研究与保健食品的开发,国家863计划(课题) 283万元,(2014-2016

  • RNA-seq策略探索新型QSI破坏耐药细菌生物被膜的分子作用机制,国家自然科学基金(面上),(2012-2015

  • 3种中国药用植物中细菌群体感应抑制剂的发现及其抗菌评价,国家自然科学基金(面上),(2011-2013

  • Quorum Sensing 为探针的3 种中国药用植物抗菌及抗耐药性研究,教育部(博士点基金-新教师类),(2009-2011

  • 以细菌群体感应为探针的3 种中国药用植物抑菌信号分子研究教育部(留学回国启动基金),(2009-2011

近年来代表性论文:

  • Liu, Y., Xie, F., Jia, A. Q. *, Li, X. W. *, (2018), Cp*Co(III)-Catalyzedamidation of olefinic and aryl C-H bonds:Highly selective synthesis of enamides and pyrimidones, Chemical Communications, 54, 4345-4348.

  • Zhou, J. W., Luo, H. Z., Jiang, H., Jian, T. K., Chen, Z. Q.,Jia, A. Q.*, (2018),Hordenine, a novel quorum sensing inhibitor and anti-biofilm agent against Pseudomonas aeruginosa, J. Agri. Food Chem.,66(7):1620-1628.

  • Yang, R., Guan, Y., Wang, W. X., Chen, H.J., He, Z.C., Jia, A.Q.*, (2018), Antioxidant capacity of phenolics in Camellia nitidissima Chi flowers and their identification by HPLC Triple TOF MS/MS, PlosOne, 13(4), e0195508.

  • Zhou, J. W., Chen, T. T., Tan, X. J., Sheng, J. Y., Jia, A. Q.*, (2018), Can resveratrol, a quorum sensing inhibitor, function as an aminoglycoside antibiotic-mate against Pseudomonas aeruginosa? International Journal of Antimicrobial Agents, 52(1), 35-41.

  • Yang, R., Zhou, J. W., Sun, B., Wang, Z. N., Chen, H. J., He, Z. C., Jia, A. Q.*, (2018), Phytochemicals from Camellia nitidissima Chi flowers reduce the pyocyanin production and motility of Pseudomonas aeruginosa PAO1, Frontiers in Microbiology, 8, 2640-2653.

  • Yang, R., Wang, W.X., Chen, H.J., He, Z.C., Jia, A.Q.*, (2018), The inhibition of advanced glycation end-products by five fractions and three main flavonoids from Camellia nitidissimaChi flowers, Journal of Food and Drug Analysis, 26, 252-259.

  • Zhou, J. W., Bi, S. Y., Chen, H. J., Chen, T. T., Yang, R., Li, M. H., Fu, Y. H., Jia, A. Q.*, (2017), Anti-Biofilm and Antivirulence Activities of Metabolites from Plectosphaerella cucumerina against Pseudomonas aeruginosa, Frontiers in Microbiology, 8, 769-786.

  • Chen, T. T., Sheng, J. Y., Fu, Y. H., Li, M. H., Wang, J. S.*, Jia, A. Q.*, (2017), 1H-NMR-Based Global Metabolic Studies of Pseudomonas aeruginosa upon Exposure of the Quorum Sensing Inhibitor Resveratrol, Journal of Proteome Research, 16 (2), 824-830.

  • Chen, X. D., Tian, D. G., Abeer, H Allah EF, A, Hu, X. Y. *, Jia, A. Q.*, (2016), The role of nitric oxide signaling in response to salt stress in Chlamydomonas reinhardtii, Planta, 244 (3), 651-69.

  • Wang, W. X., Liu, H. Y., Wang, Z. N., Qi, J., Yuan, S. T., Zhang, W. J., Chen, H. J., Finley, J. W, Gu, L. W.*, Jia, A. Q.*, (2016), Phytochemicals from Camellianitidissima Chi inhibited the formation of advanced glycation end-products by scavenging methylglyoxal, Food Chem, 205, 204-211.

  • Sheng, J. Y., Chen, T. T., Tan, X. J., Chen, T., Jia, A. Q.*, (2015), The quorum-sensing inhibiting effects of stilbenoids and their potential structure-activity relationship, Bioorganic & Medicinal Chemistry Letters, 25(22), 5217-20.

  • Xu, H. D., Wang, J. S.*, Li, M. H., Liu, Y., Chen, T., Jia, A. Q.*, (2015), 1H NMR based metabolomics approach to study the toxic effects of herbicide butachlor on goldfish (Carassius auratus). Aquatic Toxicology, 159, 69-80.

  • Wang, W. X., Qi, Y. J., Rocca, J, Sarnoski, P., Jia, A. Q.*, Gu, L. W. *, (2015),Scavenging of Toxic Acrolein by Resveratrol and Hesperetin and Identification of Adducts, J. Agri. Food Chem, 63(43), 9488-95.

  • Chen, J. H., Lin, S. S., Yuan, S. T., Shi, J. S.*, Ai-Qun Jia * (2015), The extract, LXB-1, from the barks of Liriodendron × hybrid, induced apoptosis via Akt, JNK and ERK1/2 pathways in A549 lung cancer cells, Zeitschrift für Naturforschung C (ZNC), 70 (11-12), 305-311.

  • Yang,D. T,  Lin, S. S., Chen, J. H., Yuan, S. T.,  Shi, J. S.*, Wang, J. S., Jia, A. Q.*, (2015), (+)- and (−)-liriodenol, a pair of novel enantiomeric lignans fromLiriodendron hybrid,Bioorganic & Medicinal Chemistry Letters, 25 (9), 1976-8.

  • Tan, X. J., Qin, N., Sheng, J. Y.,Peng, X. H., Jia, A. Q.* (2015),Transcriptome analysis of the biofilm formed by methicillinsusceptible Staphylococcus aureus, Scientific Reports, 5, 11997.