2015/12/24 上午10:24:28 星期四
特别鸣谢86361班校友捐赠制作环境与生物工程学院网站
师资队伍

易军

易军
教授 博士生导师

Office: 200 Xiao Ling Wei Road, Bld# 364, Rm B505

Tel: (25) 8430 3273
 
Email: yijun@njust.edu.cn

 

General:
Professor, Nanjing University of Science and Technology
Ph.D, University of Oklahoma, USA
M.S., Xiamen University,
 
Research Interests:
Heme Biomolecules, Myoglobin, Hemoglobin, Nitric Oxide, Nitrite, Heme Protein Crystallization, Bioinorganic Chemistry
 
Training:
  • Protein Purification and Characterization, Cold Spring Harbor Course
  • Computational Chemistry for Chemistry Educators, National Computational Science Institute
  • CCP4/APS School in Macromolecular Crystallography: From Data Collection to Structure Refinement and Beyond, CCP4 and Argonne National Laboratory
  • RapiData Collection and Structure Solving, National Synchrotron Light Source
Publication:
  • “Crystallographic Characterization of the Nitric Oxide Derivative of R-state Human Hemoglobin.” Yi, J.; Soares, A. S.; Richter-Addo, G. B. Nitric Oxide: Biology and Chemistry, 2014, 39, 46-50.
  • “Degradation of Human Hemoglobin by Organic C-Nitroso Compounds.” Yi J, Ye G, Thomas LM, Richter-Addo G. B. Chem. Comm., 2013, 49, 11179-11181.
  • “Nitric Oxide Coupling Mediated by Iron Porphyrins: the N-N Bond Formation Step is Facilitated by Electrons and a Proton” Yi, J.; Morrow, B. H.; Campbell, A. L.; Shen, J. K.; Richter-Addo, G. B. Chem. Comm., 2012, 48, 9041-9043.
  • “Unveiling of the Three-Dimensional Structure of the Green Pigment of Nitrite-Cured Meat” Yi, J.; Richter-Addo, G. B. Chem. Comm., 2012, 48, 4172-4174.
  • “Distal Pocket Control of Nitrite Binding in Myoglobin” Yi, J.; Thomas, L. M.; Richter-Addo, G. B, Angew. Chem. Int. Ed., 2012, 51, 3625-3627.
  • “Nitrite Reduction by CoII and MnII Substituted Myoglobins. Towards Understanding Necessary Components of Mb Nitrite Reductase Activity.” Heinecke, J.; Yi, J.; Richter-Addo, G. B.; Ford, P. C., J. Inorg. Biochem., 2011, 107, 47-53.
  • “Crystallographic Trapping of Heme Loss Intermediates During the Nitrite-Induced Degradation of Human Hemoglobin.” Yi, J.; Thomas, L. M.; Musayev, F. N.; Safo, M. K; Richter-Addo, G. B. Biochemistry, 2011, 50, 8323-8332.    
  • “Crystal Structure of Human R-State Aquomethemoglobin at 2.0 Å Resolution.” Yi, J.; Thomas, L. M.; Richter-Addo, G. B., Acta Cryst. F. 2011, 67, 647-651.
  • “Synchrotron X-Ray-Induced Photoreduction of Ferric Myoglobin Nitrite Crystals Gives the Ferrous Derivative with Retention of the O-Bonded Nitrite Ligand.” Yi, J.; Orville, A. M.; Skinner, J.; Skinner, M.; Richter-Addo, G. B. Biochemistry 2010, 49, 5969-5971.
  • “Linkage Isomerization in Heme–NOx Compounds: Understanding NO, Nitrite, and Hyponitrite Interactions with Iron Porphyrins.” Xu, N.; Yi, J.; Richter-Addo, G. B. Inorg. Chem. 2010, 49, 6253-6266.
  • “The Distal Pocket Histidine Residue in Horse Heart Myoglobin Directs the O-Binding Mode of Nitrite to the Heme Iron.” Yi, J.; Heinecke, J.; Tan, H.; Ford, P. C.; Richter-Addo, G. B. J. Am. Chem. Soc. 2009, 131, 18119-18128.
  • “Simultaneous Gas-Phase Detection of Nitric Oxide (NO) and Nitrous Oxide (N2O) from the Decomposition of Angeli's Salt (Na2N2O3) at Different pHs Using Tunable-diode Laser Absorption Spectroscopy.” Yi, J.; Namjou, K.; McCann, P. J.; Richter-Addo, G. B. Am. J. Biomed. Sci. 2009, 1, 38-46.
  • “Nano-Materials and Nano-Architecture in Heterogenous Catalysis.” Liao D. W.; Lin, J. D.; Yi, J.; Petrochemical Technology. 2009, 38, 348-355.
·         “The Nitrite Anion Binds to Human Hemoglobin via the Uncommon O-Nitrito Mode.” Yi, J.; Safo, M. K.; Richter-Addo, G. B. Biochemistry 2008, 47, 8247-8249.
  • “Specific Detection of Gaseous NO and 15NO in the Headspace of Liquid-phase Reactions Involving NO-Generating Organic, Inorganic, and Biochemical Samples Using a Mid-Infrared Laser.” Yi, J.; Namjou, K.; Zahran, Z. N.; McCann, P. J.; Richter-Addo, G. B. Nitric Oxide: Biology and Chemistry, 2006, 15, 154-162.
·         “The Solid State Molecular Structure of the S-Nitroso Derivative of L-Cysteine Ethyl Ester Hydrochloride.” Yi, J.; Khan, M. A.; Lee, J.; Richter-Addo, G. B. Nitric Oxide: Biology and Chemistry, 2005, 12, 261-266.
 
Funding:
·         江苏特聘教授人才项目(2014.01-2016.12)
·         国家自然科学基金面上项目: 哺乳类动物中血红素蛋白调控的硫化物新陈代谢机理, (2013.01-2016.12)
·         国家自然科学基金青年项目: 人体血红蛋白-亚硝基化合物的结构生物学研究, (2013.01-2015.12)